Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-493

Overview: Chronic kidney disease (CKD) is increasingly managed in primary care—but are you up to date on the latest guidance? This episode reviews current clinical practice guidelines and standards of care to help you confidently diagnose and classify CKD, apply evidence-based management strategies, and know when nephrology referral is warranted.

Episode resource links:

• https://doi.org/10.7326/ANNALS-25-03499
• Diabetes Care. 2024;48(Supplement_1):S239-S251. doi:10.2337/dc25-S011

Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos

Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com

The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Overview: In this podcast, hear from someone who will share his personal experiences with brain aneurysm diagnosis, treatment, and management — offering valuable insights into what primary care physicians can do to identify and refer patients with brain aneurysms before rupture occurs.

Overview: Listen in as expert faculty explore the neuroendocrine drivers of vasomotor symptoms (VMS)—including the KNDy neuron system—and review the efficacy and safety of emerging nonhormonal treatments. Expand your toolkit to deliver more informed, up-to-date care to patients experiencing menopause.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-492

Overview: Small lifestyle changes can yield outsized results—and primary care clinicians are ideally positioned to drive that change. This episode explores the synergistic effects of the SPAN approach on lifespan and provides actionable strategies for guiding patients toward sustainable habits that improve long-term health.

Episode resource links:

• Koemel, et al; eClinicalMedicine, Volume 0, Issue 0, 103741, 2026

Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos

Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com

The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-491

Overview: Pulse oximetry is a cornerstone of patient monitoring, but limits to its accuracy can lead to important clinical implications. Tune in as we discuss the factors that can compromise oximetry accuracy—including skin tone—so you can make more informed, individualized treatment decisions.

Episode resource links:

• Martin DS, Doidge JC, Gould D, et al. The impact of skin tone on performance of pulse oximeters used by NHS England COVID Oximetry @home scheme: measurement and diagnostic accuracy study. BMJ. 2026;392:e085535.

Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos

Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com

The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-490

Overview: In the US, maternal morbidity and mortality rates are among the highest in the western world, and stroke is one of the leading causes—responsible for 1 of 12 maternal deaths. This rate is estimated to be much higher in high-risk pregnancies. Join us as we discuss a recent study examining rates of maternal stroke in which 1 in 4 women with stroke experienced a missed diagnostic opportunity and hear what these findings mean for your practice.

Episode resource links:

• Haghighi N, Bourscheid RM, Shang C, et al. Identifying missed diagnostic opportunities in maternal stroke. Stroke. 2026;57(2). doi:10.1161/STROKEAHA.125.052995
• Chen Y, Shiels MS, Uribe-Leitz T, et al. 2025. Pregnancy-Related Deaths in the US, 2018-2022. JAMA Network Open.
• Lappen JR, Pettker CM, Louis JM. 2021. American Journal of Obstetrics and Gynecology. Society for Maternal-Fetal Medicine Consult Series #54: Assessing the Risk of Maternal morbidity and Mortality. American Journal of Obstetrics and Gynecology.
• Miller EC, Bello NA, Chen PR, et al 2026. Prevention and Treatment of Maternal Stroke in Pregnancy and Postpartum: A Scientific Statement from the American Heart Association. Stroke.
• Bushnell C, Kernan WN, Sharrief AZ, et al. 2024. Guideline for the Primary Prevention of Stroke: A Guideline from the American Heart Association/¬American Stroke Association. Stroke.

Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos

Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com

The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-489

Overview: Join us as we discuss lipoprotein(a) testing—including when it adds value and when it may not. We review the evidence behind this increasingly requested cardiovascular risk marker, equipping you with the knowledge to counsel patients, understand current and emerging treatment options, and optimize evidence-based strategies to reduce overall cardiovascular disease risk.

Episode resource links:

• Eur J Clin Invest. 2025 Oct 3:e70127. doi: 10.1111/eci.70127.

• Arterioscler Thromb Vasc Biol. 2022 Jan;42(1):e48-e60. doi: 10.1161/ATV.0000000000000147 Progress in Cardiovascular Diseases, 84, 2024, Pages 27-33, https://doi.org/10.1016/j.pcad.2024.05.007

Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos

Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com

The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-488

Overview: Stimulants have long been used to treat attention-deficit/hyperactivity disorder (ADHD); however, their mechanisms of action have been unclear. In this episode, we review a study on functional MRI to assess brain function in patients with ADHD, providing insight into the effects of stimulant medications.

Episode resource links:

• https://doi.org/10.1016/j.cell.2025.11.039

Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos

Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com

The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.